Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568810 | 0.91 | GAA (0.54) | MAPTUSP2KDM4EGAATP53 | |
| SCHEMBL2927089 | 0.85 | KDM4E (0.59) | MAPTUSP2KDM4EGAATP53 | |
| SCHEMBL15568434 | 0.82 | GAA (0.55) | MAPTUSP2KDM4EGAATP53 | |
| SCHEMBL2926661 | 0.82 | GAA (0.63) | MAPTUSP2KDM4EGAATP53 | |
| Hydrochloric Acid SCHEMBL5567171 | 0.81 | GAA (0.61) | MAPTUSP2KDM4EGAATP53 | |
| SCHEMBL2930159 | 0.79 | GAA (0.63) | MAPTUSP2KDM4EGAATP53 | |
| SCHEMBL29358757 | 0.78 | MAPT (0.65) | MAPTUSP2KDM4EGAATP53 | |
| SCHEMBL35916 | 0.78 | MAPT (0.65) | MAPTUSP2KDM4EGAATP53 | |
| Hydrochloric Acid SCHEMBL5566013 | 0.78 | GAA (0.61) | MAPTUSP2KDM4EGAATP53 | |
| SCHEMBL7121033 | 0.77 | KDM4E (0.42) | MAPTUSP2KDM4EGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364404-B2 | Dye composition comprising a cationic O-alkyl-substituted meta-phenylenediamine derivative | L'OREAL (FR) | 2016-06-14 | — | — | US | claimed |
| US-20150202135-A1 | DYE COMPOSITION COMPRISING A CATIONIC O-ALKYL-SUBSTITUTED META-PHENYLENEDIAMINE DERIVATIVE | L'OREAL (FR) | 2015-07-23 | — | — | US | claimed |
| EP-2885270-A1 | DYE COMPOSITION COMPRISING A CATIONIC O-ALKYL-SUBSTITUTED META-PHENYLENEDIAMINE DERIVATIVE | L'Oréal (FR) | 2015-06-24 | — | — | EP | claimed |
| WO-2014026952-A1 | DYE COMPOSITION COMPRISING A CATIONIC O-ALKYL-SUBSTITUTED META-PHENYLENEDIAMINE DERIVATIVE | L'OREAL (FR) | 2014-02-20 | — | — | WO | claimed |
| US-9364404-B2 | Dye composition comprising a cationic O-alkyl-substituted meta-phenylenediamine derivative | L'OREAL (FR) | 2016-06-14 | — | — | US | disclosed |
| US-20150202135-A1 | DYE COMPOSITION COMPRISING A CATIONIC O-ALKYL-SUBSTITUTED META-PHENYLENEDIAMINE DERIVATIVE | L'OREAL (FR) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202135-A1 | DYE COMPOSITION COMPRISING A CATIONIC O-ALKYL-SUBSTITUTED META-PHENYLENEDIAMINE DERIVATIVE | MT-ND6, C5, C9 | MAPT 4160/4885USP2 4846/4885KDM4E 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.