SCHEMBL35916

SCHEMBL35916

Nc1ccc(OCCO)c(N)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.65
GAA P10253 3/20 0.65
ALDH1A1 P00352 3/20 0.65
USP2 O75604 2/20 0.65
TP53 P04637 2/20 0.65
POLB P06746 2/20 0.65
KDM4E B2RXH2 2/20 0.65
MEN1 O00255 1/20 0.65
CASP1 P29466 1/20 0.65
HTT P42858 1/20 0.65
CASP7 P55210 1/20 0.65
KMT2A Q03164 1/20 0.65
ATM Q13315 1/20 0.65
PRSS1 P07477 8/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.42
IDO1 P14902 1/20 0.42
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358757 1.00 MAPT (0.65) MAPTGAAALDH1A1USP2TP53
Ammonia Solution, Strong SCHEMBL27977263 0.98 MAPT (0.62) MAPTGAAALDH1A1USP2TP53
Hydrochloric Acid SCHEMBL33976 0.98 GAA (0.68) MAPTGAAALDH1A1USP2TP53
Hydrochloric Acid SCHEMBL29378616 0.98 GAA (0.68) MAPTGAAALDH1A1USP2TP53
Hydrochloric Acid SCHEMBL29356501 0.98 GAA (0.68) MAPTGAAALDH1A1USP2TP53
Hydrochloric Acid SCHEMBL1453993 0.98 GAA (0.68) MAPTGAAALDH1A1USP2TP53
Hydrochloric Acid SCHEMBL22612486 0.96 MAPT (0.61) MAPTGAAALDH1A1USP2TP53
SCHEMBL8091658 0.96 MAPT (0.61) MAPTGAAALDH1A1USP2TP53
Hydrochloric Acid SCHEMBL29148900 0.96 GAA (0.66) MAPTGAAALDH1A1USP2TP53
2,4-Diaminophenol SCHEMBL19327374 0.91 ALDH1A1 (0.56) MAPTGAAALDH1A1USP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9312 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
EP-4731170-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE Wella Germany GmbH (DE) 2026-04-29 EP claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
EP-4408377-B1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KAO CORP (JP) 2025-10-08 EP claimed
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-3393431-B1 COMPOSITION FOR DYEING THE HAIR, COMPRISING AN OXIDATION BASE, A 2-AMINO-5-ETHYLPHENOL COUPLER AND A FATTY SUBSTANCE OREAL (FR) 2025-07-23 EP claimed
US-4563188-A SHADES OF GREEN L'OREAL (FR) 1986-01-07 US claimed
EP-0166155-A1 2-Alkylsulphonyl-1,4-diaminobenzenes, process for their preparation and oxidative hair-dyeing compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
US-4473375-A COUPLER AND DEVELOPER FOR OXIDATION COLOR DYES WELLA AKTIENGESELLSCHAFT (DE) 1984-09-25 US claimed
US-4333730-A HAIR DYES SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-08 US claimed
US-4330292-A CONTAINING AN OXIDATION BASE L'OREAL (FR) 1982-05-18 US claimed
US-4324553-A OXIDATION COLOR DYES L'OREAL (FR) 1982-04-13 US claimed
US-4323360-A Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent L'OREAL (FR) 1982-04-06 US claimed
US-4305717-A P-PHENYLENEDIAMINE OXIDIZING BASE AND COUPLER TO FORM INDAMINES L'OREAL (FR) 1981-12-15 US claimed
US-4149848-A N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES L'OREAL (FR) 1979-04-17 US claimed
US-4094635-A Meta-aminophenol sulfonamides as couplers in hair dye compositions L'OREAL (FR) 1978-06-13 US claimed