Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032479 | 0.82 | KDM4E (0.78) | KDM4ETDP1LMNASMN1; SMN2CLCN2 | |
| SCHEMBL15569110 | 0.81 | KDM4E (0.53) | KDM4ETDP1LMNASMN1; SMN2CLCN2 | |
| SCHEMBL270419 | 0.79 | KDM4E (1.00) | KDM4ETDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30639818 | 0.77 | KDM4E (0.95) | KDM4ETDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30639802 | 0.77 | KDM4E (0.95) | KDM4ETDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29723448 | 0.77 | KDM4E (0.95) | KDM4ETDP1LMNASMN1; SMN2ALDH1A1 | |
| Dipyridyl SCHEMBL3957151 | 0.73 | KDM4E (0.62) | KDM4ETDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL17201771 | 0.73 | KDM4E (0.47) | KDM4ETDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31190966 | 0.73 | KDM4E (0.53) | KDM4ETDP1LMNASMN1; SMN2CLCN2 | |
| SCHEMBL18425125 | 0.72 | MYC (0.40) | KDM4ESMN1; SMN2CLCN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882732-B1 | HERBICIDALLY ACTIVE DERIVATIVES OF 6'-PHENYL-2,2'-BIPYRIDIN-3-CARBOXYLIC ACID | BAYER CROPSCIENCE AG (DE) | 2017-04-12 | — | — | EP | disclosed |
| EP-2882732-A1 | HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023670-A1 | HERBICIDALLY ACTIVE 6'-PHENYL-2,2'-BIPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-02-13 | — | — | WO | disclosed |