Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | AGER | Q15109 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MYC | P01106 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL3957151 | 0.89 | KDM4E (0.62) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL270419 | 0.88 | KDM4E (1.00) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL30639818 | 0.86 | KDM4E (0.95) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL30639802 | 0.86 | KDM4E (0.95) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL29723448 | 0.86 | KDM4E (0.95) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL30555267 | 0.84 | KDM4E (0.59) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL10000544 | 0.84 | KDM4E (0.65) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6876755 | 0.84 | KDM4E (0.59) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL15569130 | 0.82 | KDM4E (0.62) | KDM4ETDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL7847715 | 0.80 | KDM4E (0.54) | KDM4ETDP1ALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003003009-A1 | USE OF METAL-ION CHELATES IN VALIDATING BIOLOGICAL MOLECULES AS DRUG TARGETS IN TEST ANIMAL MODELS | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |