Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.57 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.57 |
| ▸ | GSR | P00390 | 2/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norvaline SCHEMBL15570206 | 1.00 | GRIK1 (0.57) | GRIK1SLC1A2SLC1A1GRIK2SLC1A3 | |
| Norleucine SCHEMBL1053852 | 0.87 | SLC1A2 (0.62) | GRIK1SLC1A2SLC1A1GRIK2SLC1A3 | |
| Norleucine SCHEMBL1053849 | 0.87 | SLC1A2 (0.62) | GRIK1SLC1A2SLC1A1GRIK2SLC1A3 | |
| Norvaline SCHEMBL38405 | 0.87 | — | — | |
| Norvaline SCHEMBL840389 | 0.87 | SLC1A2 (0.64) | GRIK1SLC1A2SLC1A1GRIK2SLC1A3 | |
| Norvaline SCHEMBL17449755 | 0.87 | — | — | |
| Norvaline SCHEMBL38404 | 0.87 | — | — | |
| Norvaline SCHEMBL197812 | 0.87 | — | — | |
| Norvaline SCHEMBL21114359 | 0.87 | SLC1A2 (0.64) | GRIK1SLC1A2SLC1A1GRIK2SLC1A3 | |
| Norvaline SCHEMBL542602 | 0.87 | SLC1A2 (0.64) | GRIK1SLC1A2SLC1A1GRIK2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885415-A1 | TWO STAGE PRODUCTION OF HIGHER ALCOHOLS | Easel Biotechnologies LLC (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014028642-A1 | TWO STAGE PRODUCTION OF HIGHER ALCOHOLS | EASEL BIOTECHNOLOGIES, LLC (US) | 2014-02-20 | — | — | WO | disclosed |