Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570361 | 1.00 | FNTA (0.42) | FNTAFNTBTHRBPGGT1BLMNA | |
| SCHEMBL18279538 | 0.87 | LMNA (0.48) | LMNAALDH1A1HSD17B10ALDH2KDM4E | |
| SCHEMBL18279540 | 0.87 | LMNA (0.48) | LMNAALDH1A1HSD17B10ALDH2KDM4E | |
| SCHEMBL15667962 | 0.85 | LMNA (0.36) | FNTAFNTBTHRBPGGT1BLMNA | |
| SCHEMBL23646014 | 0.78 | FNTA (0.41) | FNTAFNTBTHRBPGGT1BALDH1A1 | |
| SCHEMBL18700396 | 0.74 | LMNA (0.44) | LMNAALDH1A1HSD17B10ALDH2KDM4E | |
| SCHEMBL2097527 | 0.74 | LMNA (0.60) | LMNAALDH1A1HSD17B10ALDH2GAA | |
| SCHEMBL14874370 | 0.73 | FNTA (0.43) | FNTAFNTBTHRBPGGT1BHSD17B10 | |
| SCHEMBL15512105 | 0.73 | LMNA (0.48) | LMNAALDH1A1HSD17B10ALDH2KDM4E | |
| SCHEMBL1333039 | 0.72 | FNTA (0.46) | FNTAFNTBTHRBPGGT1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031897-A1 | ORAL DOSAGE FORMS HAVING A HIGH LOADING OF (N,N- DIETHYLCARBAMOYL)METHYL METHYL|(2E)BUT-2-ENE-1,4-DIOATE | XENOPORT, INC. (US) | 2014-02-27 | — | — | WO | disclosed |