Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097527 | 0.77 | LMNA (0.60) | LMNAHSD17B10ALDH1A1ALDH2MMP1 | |
| SCHEMBL15512105 | 0.76 | LMNA (0.48) | LMNAHSD17B10ALDH1A1ALDH2KDM4E | |
| SCHEMBL18279538 | 0.76 | LMNA (0.48) | LMNAHSD17B10ALDH1A1ALDH2KDM4E | |
| SCHEMBL18279540 | 0.76 | LMNA (0.48) | LMNAHSD17B10ALDH1A1ALDH2KDM4E | |
| SCHEMBL5282077 | 0.76 | ALOX15 (0.43) | HSD17B10ALOX15ALDH1A1TET2TET3 | |
| SCHEMBL11189562 | 0.75 | LMNA (0.52) | LMNAHSD17B10ALDH1A1ALDH2MMP1 | |
| SCHEMBL17284813 | 0.75 | TET2 (0.36) | HSD17B10ALOX15TET2TET3TET1 | |
| SCHEMBL15570361 | 0.74 | FNTA (0.42) | LMNAHSD17B10ALDH1A1ALDH2KDM4E | |
| SCHEMBL11057516 | 0.74 | ALDH1A1 (0.52) | LMNAHSD17B10ALOX15ALDH1A1TET2 | |
| SCHEMBL15570359 | 0.74 | FNTA (0.42) | LMNAHSD17B10ALDH1A1ALDH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066113-A9 | AMINOSILOXANE POLYMER AND METHOD OF FORMING | DOW SILICONES CORPORATION | 2018-03-08 | — | — | US | disclosed |
| US-20170096533-A1 | AMINOSILOXANE POLYMER AND METHOD OF FORMING | DOW CORNING (US) | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066113-A9 | AMINOSILOXANE POLYMER AND METHOD OF FORMING | HRH3, H1-2, H1-0 | LMNA 1867/4885HSD17B10 476/4885ALOX15 499/4885 |
| US-20170096533-A1 | AMINOSILOXANE POLYMER AND METHOD OF FORMING | HRH3, H1-2, H1-0 | LMNA 1867/4885HSD17B10 476/4885ALOX15 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.