SCHEMBL15570720

SCHEMBL15570720

CC(C)C(N)CO[N+](=O)[O-]

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
SCN4A P35499 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28728503 0.98 ALDH1A1 (0.34) ALDH1A1SCN4ACYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL7861505 0.98 ALDH1A1 (0.34) ALDH1A1SCN4ACYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL8524602 0.98 ALDH1A1 (0.34) ALDH1A1SCN4ACYP1A2CYP3A4CYP2D6
SCHEMBL15570722 0.81 SCN4A (0.35) SCN4ACYP1A2CYP3A4CYP2D6NFKB1
SCHEMBL7849326 0.81
SCHEMBL8297383 0.81
Hydrochloric Acid SCHEMBL7845461 0.79
Hydrochloric Acid SCHEMBL7860682 0.79
Hydrochloric Acid SCHEMBL7861087 0.79
Nitric Acid SCHEMBL9204401 0.76 PTGS2 (0.35) ALDH1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107311973-B Nitrate-group-containing dihydromyricetin derivative and preparation and application thereof 石家庄学院 2021-04-06 CN disclosed
EP-2887927-B1 EXTENDED RELEASE COMPOSITIONS OF AN AMINO-C2-C6-ALKYL NITRATE CARDIOLYNX AG (CH) 2018-03-28 EP disclosed
US-20180036259-A1 NO DONORS FOR THE TREATMENT OF IMPAIRED TISSUE PERFUSION MIRANDAPHARMACEUTICALS AG (CH) 2018-02-08 US disclosed
US-20180008558-A1 EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE CARDIOLYNX AG (CH) 2018-01-11 US disclosed
US-20170100350-A1 EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE CARDIOLYNX AG (CH) 2017-04-13 US disclosed
WO-2016135262-A1 NO DONORS FOR THE TREATMENT OF IMPAIRED TISSUE PERFUSION CARDIOLYNX AG (CH) 2016-09-01 WO disclosed
WO-2016135263-A1 NO DONORS FOR THE TREATMENT OF STRESS-INDUCED PULMONARY HAEMORRHAGE IN ANIMALS SCHERHAG ARMIN (CH) 2016-09-01 WO disclosed
CN-104869985-A Extended release compositions of an aminoalkyl nitrate CARDIOLYNX AG 2015-08-26 CN disclosed
US-20150216992-A1 EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE CARDIOLYNX AG (CH) 2015-08-06 US disclosed
EP-2887927-A1 EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE Cardiolynx AG (CH) 2015-07-01 EP disclosed
WO-2014029841-A1 EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE CARDIOLYNX AG (CH) 2014-02-27 WO disclosed