Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.68 |
| ▸ | MEN1 | O00255 | 12/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.68 |
| ▸ | MAPT | P10636 | 11/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | BRCA1 | P38398 | 4/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | PRNP | P04156 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 10/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15571632 | 0.79 | MEN1 (0.68) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21043625 | 0.77 | MEN1 (1.00) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15572874 | 0.77 | MEN1 (0.68) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15572213 | 0.74 | EEF2K (1.00) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15572039 | 0.72 | CUL4A (1.00) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21043628 | 0.71 | CUL4A (1.00) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7815153 | 0.71 | KDM4E (0.60) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL26121762 | 0.71 | CUL4A (0.54) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6441000 | 0.71 | KMT2A (0.55) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13295965 | 0.69 | CUL4A (0.53) | CUL4AALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10617683-B2 | Inhibitors of CRL4 ubiquitin ligase and uses thereof | CORNELL UNIVERSITY (US) | 2020-04-14 | — | — | US | claimed |
| US-20150196546-A1 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | CORNELL UNIVERSITY | 2015-07-16 | — | — | US | claimed |
| EP-2887940-A2 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | Cornell University (US) | 2015-07-01 | — | — | EP | claimed |
| WO-2014031759-A2 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | CORNELL UNIVERSITY (US) | 2014-02-27 | — | — | WO | claimed |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| CN-104968323-B | CRL4 ubiquitin ligase inhibitors and uses thereof | 康奈尔大学 | 2020-08-21 | — | — | CN | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-10617683-B2 | Inhibitors of CRL4 ubiquitin ligase and uses thereof | CORNELL UNIVERSITY (US) | 2020-04-14 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| EP-2887940-B1 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | UNIV CORNELL (US) | 2019-06-05 | — | — | EP | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| US-20150196546-A1 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | CORNELL UNIVERSITY | 2015-07-16 | — | — | US | disclosed |
| EP-2887940-A2 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | Cornell University (US) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014201326-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014031759-A2 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | CORNELL UNIVERSITY (US) | 2014-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | CUL4A 857/4885ALDH1A1 1039/4885MEN1 4484/4885 |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | CUL4A 857/4885ALDH1A1 1039/4885MEN1 4484/4885 |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | CUL4A 857/4885ALDH1A1 1039/4885MEN1 4484/4885 |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | CUL4A 857/4885ALDH1A1 1039/4885MEN1 4484/4885 |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | CUL4A 857/4885ALDH1A1 1039/4885MEN1 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.