Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 9/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 6/20 | 1.00 |
| ▸ | KDR | P35968 | 6/20 | 1.00 |
| ▸ | MAP3K11 | Q16584 | 6/20 | 1.00 |
| ▸ | MAP3K9 | P80192 | 5/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 4/20 | 1.00 |
| ▸ | PRKCG | P05129 | 4/20 | 1.00 |
| ▸ | PRKCB | P05771 | 4/20 | 1.00 |
| ▸ | PRKCA | P17252 | 4/20 | 1.00 |
| ▸ | PRKCH | P24723 | 4/20 | 1.00 |
| ▸ | PRKCI | P41743 | 4/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 4/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 4/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 4/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 4/20 | 1.00 |
| ▸ | MAP3K10 | Q02779 | 4/20 | 1.00 |
| ▸ | MYLK | Q15746 | 3/20 | 1.00 |
| ▸ | CDK4 | P11802 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| K-252A SCHEMBL29434956 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL31181849 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL29355962 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL32665760 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL13993461 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL13787898 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL24112155 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL13485248 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL968886 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 | |
| K-252A SCHEMBL29660621 | 1.00 | NTRK1 (1.00) | NTRK1PRKCQKDRMAP3K11MAP3K9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567102-A1 | METHODS FOR ISOLATING EMBRYONIC STEM CELLS FROM AVIAN EMBRYONIC CELLS | Suprême (FR) | 2025-06-11 | — | — | EP | disclosed |
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION | 2023-09-14 | — | — | US | disclosed |
| WO-2023039578-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION (US) | 2023-03-16 | — | — | WO | disclosed |
| CN-110468051-B | K252A fermentation medium and preparation method thereof | 海正药业(杭州)有限公司 | 2022-08-23 | — | — | CN | disclosed |
| US-20210322439-A1 | COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH RTK MUTANT CELLS | IGNYTA, INC. (US) | 2021-10-21 | — | — | US | disclosed |
| CN-110468051-A | A kind of K252A fermentation medium and preparation method thereof | HISUN PHARMACEUTICAL HANGZHOU CO LTD | 2019-11-19 | — | — | CN | disclosed |
| US-10094834-B2 | Method of selecting individualized brain cancer therapy | TURUN YLIOPISTO (FI) | 2018-10-09 | — | — | US | disclosed |
| US-20180177792-A1 | COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH RTK MUTANT CELLS | IGNYTA, INC. (US) | 2018-06-28 | — | — | US | disclosed |
| CN-104755936-B | The method of the personalized cancer of the brain therapy of selection | 图尔库大学 | 2018-04-27 | — | — | CN | disclosed |
| US-9918989-B2 | Combination therapies for malaria | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-20 | — | — | US | disclosed |
| CN-105727296-A | Medicine for killing tumor cells and stem cells thereof and preparation method thereof | 昆明医科大学 | 2016-07-06 | — | — | CN | disclosed |
| US-20160151380-A1 | THERAPIES FOR DISEASES CAUSED BY ARTHROPOD-BORNE PARASITES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-06-02 | — | — | US | disclosed |
| US-20160151379-A1 | COMBINATION THERAPIES FOR MALARIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-06-02 | — | — | US | disclosed |
| EP-2723450-B1 | COMBINATION THERAPY | TURUN YLIOPISTO (FI) | 2016-05-18 | — | — | EP | disclosed |
| US-20150204877-A1 | METHOD OF SELECTING INDIVIDUALIZED BRAIN CANCER THERAPY | TURUN YLIOPISTO (FI) | 2015-07-23 | — | — | US | disclosed |
| EP-2890986-A1 | METHOD OF SELECTING INDIVIDUALIZED BRAIN CANCER THERAPY | Turun Yliopisto (FI) | 2015-07-08 | — | — | EP | disclosed |
| CN-104755936-A | Method of selecting individualized brain cancer therapy | TURUN YLIOPISTO | 2015-07-01 | — | — | CN | disclosed |
| CN-104619845-A | Combination therapy iii | TURUN YLIOPISTO | 2015-05-13 | — | — | CN | disclosed |
| WO-2015006752-A1 | COMBINATION THERAPIES FOR MALARIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-01-15 | — | — | WO | disclosed |
| WO-2014033367-A1 | METHOD OF SELECTING INDIVIDUALIZED BRAIN CANCER THERAPY | TURUN YLIOPISTO (FI) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | TP53, CD4, MCL1 | NTRK1 4199/4885PRKCQ 1247/4885KDR 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.