Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 10/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577211 | 0.89 | DRD2 (0.55) | DRD2HTR1ADRD3 | |
| SCHEMBL7919530 | 0.85 | ACHE (0.37) | DRD2HTR1A | |
| SCHEMBL29320876 | 0.84 | DRD2 (0.40) | DRD2HTR1A | |
| SCHEMBL266635 | 0.81 | DRD2 (0.50) | DRD2HTR1ADRD3HCRTR1HCRTR2 | |
| SCHEMBL29428654 | 0.80 | PDE7A (0.39) | — | |
| SCHEMBL13198514 | 0.80 | PDE7A (0.39) | — | |
| SCHEMBL20478729 | 0.79 | HCRTR1 (0.44) | DRD2HTR1AHCRTR1HCRTR2 | |
| SCHEMBL10192239 | 0.79 | DRD2 (0.43) | DRD2HTR1ADRD3HCRTR1HCRTR2 | |
| SCHEMBL9150411 | 0.79 | ACHE (0.52) | DRD2HTR1ADRD3 | |
| SCHEMBL10246358 | 0.79 | DRD2 (0.49) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674095-B2 | Compounds for treating neuropsychiatric conditions | AFRAXIS HOLDINGS, INC. (US) | 2014-03-18 | — | — | US | disclosed |