Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614787 | 1.00 | GAA (0.60) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL4148059 | 0.93 | MAPT (0.63) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL16941536 | 0.93 | GAA (0.65) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL4148681 | 0.90 | ALOX15 (0.68) | CYP2D6MAPTALOX15SMN1; SMN2MEN1 | |
| SCHEMBL16946169 | 0.88 | CYP2D6 (0.74) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL4156108 | 0.88 | CYP2D6 (0.74) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL4142828 | 0.86 | CYP2D6 (0.79) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL15614780 | 0.84 | GAA (0.59) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL4153687 | 0.84 | CYP2D6 (0.56) | GAACASP6CYP2D6MAPTALOX15 | |
| SCHEMBL4143028 | 0.84 | MAPT (0.63) | CYP2D6MAPTALOX15SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895462-A1 | SPECIFIC INHIBITORS OF PROTEIN P21 AS THERAPEUTIC AGENTS | Baden-Württemberg Stiftung gGmbH (DE) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014041125-A1 | SPECIFIC INHIBITORS OF PROTEIN P21 AS THERAPEUTIC AGENTS | BADEN-WÜRTTEMBERG STIFTUNG GMBH (DE) | 2014-03-20 | — | — | WO | disclosed |