SCHEMBL15577347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15577374	0.88	STIM1 (0.46)	CRACR2ASTIM1ORAI1TRPC1TRPC3
	SCHEMBL15577328	0.88	STIM1 (0.46)	CRACR2ASTIM1ORAI1TRPC1TRPC3
	SCHEMBL15577332	0.86	STIM1 (0.44)	CRACR2ASTIM1ORAI1TRPC1TRPC3
	SCHEMBL15577339	0.85	CRHR1 (0.49)	CRHR1CRHR2CRACR2A
	SCHEMBL15577493	0.85	STIM1 (0.48)	CRACR2ASTIM1ORAI1TRPC1TRPC3
	SCHEMBL15577407	0.84	STIM1 (0.43)	CRACR2ASTIM1ORAI1TRPC1TRPC3
	SCHEMBL15577426	0.84	CRACR2A (0.48)	CRACR2ASTIM1ORAI1TRPC1TRPC3
	SCHEMBL15579179	0.84	CRACR2A (0.42)	CRHR1CRHR2CRACR2ASTIM1ORAI1
	SCHEMBL15606063	0.83	CRACR2A (0.41)	CRHR1CRHR2CRACR2ASTIM1ORAI1
	SCHEMBL15577410	0.83	STIM1 (0.42)	CRACR2ASTIM1ORAI1TRPC1TRPC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.