Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | HTR1A | P08908 | 9/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844136 | 0.91 | SLC6A2 (0.37) | SLC6A2SLC6A4HTR1ASLC6A3NMT1 | |
| SCHEMBL19318462 | 0.88 | DPP4 (0.41) | DPP4 | |
| Hydrochloric Acid SCHEMBL4795570 | 0.86 | DPP4 (0.40) | DPP4 | |
| Tert-Butyl Formate SCHEMBL27841198 | 0.86 | SLC6A2 (0.38) | SLC6A2SLC6A4HTR1ASLC6A3NMT1 | |
| SCHEMBL11867879 | 0.78 | SLC6A2 (0.37) | SLC6A2SLC6A4HTR1ASLC6A3NMT1 | |
| Hydrochloric Acid SCHEMBL22031737 | 0.77 | HTR1A (0.43) | SLC6A2SLC6A4HTR1ASLC6A3SLC18A3 | |
| SCHEMBL11865375 | 0.76 | NMT1 (0.37) | SLC6A2SLC6A4HTR1ASLC6A3NMT1 | |
| SCHEMBL12210718 | 0.75 | KDM4E (0.46) | NMT1 | |
| SCHEMBL13239364 | 0.75 | SLC6A4 (0.54) | SLC6A2SLC6A4HTR1ASLC6A3SLC18A3 | |
| SCHEMBL3212767 | 0.75 | HTR1A (0.55) | SLC6A2SLC6A4HTR1ASLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303859-A2 | ARYL GPR119 AGONISTS AND USES THEREOF | Metabolex Inc. (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010008739-A2 | ARYL GPR119 AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2010-01-21 | — | — | WO | disclosed |