SCHEMBL8844136

SCHEMBL8844136

NCc1cccnc1C1CCNC1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.37
SLC6A4 P31645 4/20 0.37
SLC6A3 Q01959 4/20 0.37
HTR1A P08908 1/20 0.37
HTR3A P46098 1/20 0.36
NMT1 P30419 1/20 0.36
CXCR4 P61073 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1557767 0.91 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3HTR1ANMT1
SCHEMBL19318462 0.82 DPP4 (0.41) CXCR4
Hydrochloric Acid SCHEMBL4795570 0.80 DPP4 (0.40) CXCR4
SCHEMBL8844155 0.80 HTR1A (0.39) SLC6A2SLC6A4SLC6A3HTR1AHTR3A
Methane SCHEMBL9482819 0.78 HTR1A (0.38) SLC6A2SLC6A4SLC6A3HTR1AHTR3A
Tert-Butyl Formate SCHEMBL27841198 0.78 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3HTR1ANMT1
SCHEMBL29229133 0.76 OPRM1 (0.41) SLC6A2SLC6A4SLC6A3HTR1AHTR3A
SCHEMBL2461209 0.74 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3HTR1A
SCHEMBL21460222 0.74 PARP1 (0.53)
SCHEMBL30421966 0.71 HTR3A (0.33) SLC6A2SLC6A4SLC6A3HTR1AHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5622966-A BACTERICIDES TREATING INFECTIONS WARNER-LAMBERT COMPANY (US) 1997-04-22 US disclosed
US-5446044-A Bactericides WARNER-LAMBERT COMPANY (US) 1995-08-29 US disclosed
US-5384407-A Pyrrolidine compounds WARNER-LAMBERT COMPANY (US) 1995-01-24 US disclosed
US-5342844-A 7-substituted quinolones and naphthyridones as antibacterial agents WARNER-LAMBERT COMPANY (US) 1994-08-30 US disclosed
WO-1993016077-A1 7-SUBSTITUTED QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 1993-08-19 WO disclosed
US-5221676-A 7-substituted quinolones and naphthyridones as antibacterial agents WARNER-LAMBERT COMPANY (US) 1993-06-22 US disclosed