Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 18/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15580255 | 0.83 | HDAC3 (1.00) | HDAC1HDAC3HDAC6HDAC8HDAC7 | |
| SCHEMBL19114280 | 0.77 | HDAC1 (0.74) | HDAC1HDAC3HDAC6HDAC8HDAC7 | |
| SCHEMBL19114550 | 0.76 | HDAC1 (0.69) | HDAC1HDAC3HDAC6HDAC8HDAC7 | |
| SCHEMBL15580223 | 0.75 | HDAC3 (1.00) | HDAC1HDAC3HDAC6HDAC8HDAC7 | |
| SCHEMBL15580281 | 0.74 | HDAC1 (0.53) | HDAC1HDAC3HDAC6HDAC8 | |
| SCHEMBL15580193 | 0.72 | HDAC1 (0.89) | HDAC1HDAC3HDAC6HDAC8HDAC7 | |
| SCHEMBL21663724 | 0.70 | HDAC1 (0.49) | HDAC1HDAC3HDAC6HDAC8 | |
| SCHEMBL21663988 | 0.70 | HDAC1 (0.49) | HDAC1HDAC3HDAC6HDAC8 | |
| SCHEMBL13297066 | 0.69 | RAB9A (0.59) | HDAC1HDAC3HDAC6 | |
| SCHEMBL15580192 | 0.69 | HDAC1 (0.79) | HDAC1HDAC3HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2708534-A1 | THIAZOLE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Puyi Chemical Co., Ltd. (CN) | 2014-03-19 | — | — | EP | disclosed |