Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM4B | O94953 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21663988 | 0.81 | HDAC1 (0.49) | HDAC1HDAC6HDAC3KDM4EACHE | |
| SCHEMBL21663724 | 0.81 | HDAC1 (0.49) | HDAC1HDAC6HDAC3KDM4EACHE | |
| SCHEMBL6786585 | 0.79 | ALDH1A1 (0.63) | HDAC1HDAC6KDM4EALDH1A1HPGDS | |
| SCHEMBL13297066 | 0.77 | RAB9A (0.59) | HDAC1HDAC6HDAC3ALDH1A1 | |
| SCHEMBL15580301 | 0.74 | HDAC1 (0.71) | HDAC1HDAC6HDAC3HDAC8 | |
| SCHEMBL19114550 | 0.73 | HDAC1 (0.69) | HDAC1HDAC6HDAC3HDAC8 | |
| SCHEMBL13368619 | 0.73 | ALDH1A1 (0.46) | HDAC1HDAC6KDM4EALDH1A1HPGDS | |
| SCHEMBL2550713 | 0.73 | PDE10A (0.57) | KDM4EALDH1A1HPGDSACHEKDM4A | |
| SCHEMBL1999671 | 0.73 | HDAC1 (0.71) | HDAC1HDAC6KDM4EALDH1A1HPGDS | |
| SCHEMBL1817599 | 0.73 | ALDH1A1 (0.46) | HDAC1HDAC6KDM4EALDH1A1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
| CN-114599662-A | Neomycin-based compounds and pharmaceutical uses thereof | 蔚蓝海岸大学 | 2022-06-07 | — | — | CN | disclosed |
| EP-2708534-B1 | THIAZOLE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANGHAI THEORION PHARMACEUTICAL CO LTD (CN) | 2017-07-12 | — | — | EP | disclosed |
| US-9216962-B2 | Thiazole compounds, methods for preparation and use thereof | SHANGHAI PUYI CHEMICAL CO., LTD. (CN) | 2015-12-22 | — | — | US | disclosed |
| US-9216962-B2 | Thiazole compounds, methods for preparation and use thereof | SHANGHAI PUYI CHEMICAL CO., LTD. (CN) | 2015-12-22 | — | — | US | disclosed |
| US-20140148600-A1 | THIAZOLE COMPOUNDS, METHODS FOR PREPARATION AND USE THEREOF | SHANGHAI THEORION PHARMACEUTICAL CO., LTD. (CN) | 2014-05-29 | — | — | US | disclosed |
| US-20140148600-A1 | THIAZOLE COMPOUNDS, METHODS FOR PREPARATION AND USE THEREOF | SHANGHAI THEORION PHARMACEUTICAL CO., LTD. (CN) | 2014-05-29 | — | — | US | disclosed |
| EP-2708534-A1 | THIAZOLE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Puyi Chemical Co., Ltd. (CN) | 2014-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP9, DPP7, DPP4 | HDAC1 312/4885HDAC6 718/4885HDAC3 146/4885 |
| US-20140148600-A1 | THIAZOLE COMPOUNDS, METHODS FOR PREPARATION AND USE THEREOF | HDAC5, HDAC7, HDAC1 | HDAC1 3/4885HDAC6 7/4885HDAC3 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.