Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 4/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15580424 | 0.91 | PPARA (0.42) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL5237487 | 0.90 | KMT2A (0.43) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL14416216 | 0.90 | KMT2A (0.43) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL14416217 | 0.87 | KLK7 (0.43) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL15306512 | 0.84 | SYK (0.43) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL296601 | 0.84 | SYK (0.43) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL7936447 | 0.83 | OPRM1 (0.44) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL5235644 | 0.82 | SYK (0.41) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL18506635 | 0.82 | CA12 (0.42) | PPARAKMT2AL3MBTL1EPHX2KLK7 | |
| SCHEMBL17691231 | 0.81 | EPHX2 (0.42) | PPARAKMT2AL3MBTL1EPHX2KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172459-B1 | COMPOUND HAVING HYDANTOIN RING AND METHOD OF PRODUCING THE SAME | TOKUYAMA CORP (JP) | 2014-03-19 | — | — | EP | disclosed |