SCHEMBL296601

SCHEMBL296601

CCOC(=O)C1(NC(=O)OC(C)(C)C)CC(OCc2ccccc2)C1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.43
AKT1 P31749 3/20 0.41
EPHX2 P34913 1/20 0.41
ADAM17 P78536 1/20 0.41
KLK7 P49862 5/20 0.41
KLK5 Q9Y337 3/20 0.41
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CTSL P07711 3/20 0.39
CTSB P07858 2/20 0.38
CTSS P25774 2/20 0.38
PPARA Q07869 1/20 0.38
ABCB1 P08183 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15306512 1.00 SYK (0.43) SYKAKT1EPHX2ADAM17KLK7
SCHEMBL14416217 0.90 KLK7 (0.43) SYKAKT1EPHX2ADAM17KLK7
SCHEMBL5235644 0.89 SYK (0.41) SYKAKT1EPHX2KLK7KLK5
SCHEMBL14416216 0.88 KMT2A (0.43) SYKAKT1EPHX2KLK7KLK5
SCHEMBL5237487 0.88 KMT2A (0.43) SYKAKT1EPHX2KLK7KLK5
SCHEMBL5235374 0.87 KLK7 (0.40) SYKEPHX2KLK7KLK5KMT2A
SCHEMBL22414341 0.85 PPARA (0.41) SYKAKT1ADAM17KLK7KLK5
SCHEMBL20341630 0.85 PPARA (0.41) SYKAKT1ADAM17KLK7KLK5
SCHEMBL15580417 0.84 PPARA (0.44) SYKAKT1EPHX2KLK7KLK5
SCHEMBL15580424 0.84 PPARA (0.42) SYKAKT1EPHX2KLK7KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3354639-B1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2024-02-21 EP disclosed
EP-3530648-B1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2023-11-08 EP disclosed
US-20210386873-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2021-12-16 US disclosed
US-11083804-B2 Precursor compound of radioactive halogen-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2021-08-10 US disclosed
US-10953112-B2 Precursor compound of radioactive halogen-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2021-03-23 US disclosed
US-20200282082-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2020-09-10 US disclosed
EP-3530648-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD (JP) 2019-08-28 EP disclosed
EP-2128130-B1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2018-10-10 EP disclosed
US-20180256760-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2018-09-13 US disclosed
EP-3354639-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2018-08-01 EP disclosed
EP-2017258-B1 PROCESS FOR PRODUCTION OF RADIOACTIVE FLUORINE-LABELED ORGANIC COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2012-03-14 EP disclosed
US-7897811-B2 Process for production of radioactive fluorine-labeled organic compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2011-03-01 US disclosed
US-20100261931-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2010-10-14 US disclosed
EP-2230229-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2010-09-22 EP disclosed
US-20100016626-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2010-01-21 US disclosed
EP-2128130-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2009-12-02 EP disclosed
US-20090198085-A1 Process for Production of Radioactive Fluorine-Labeled Organic Compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2009-08-06 US disclosed
EP-2017258-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE FLUORINE-LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2009-01-21 EP disclosed
US-20080281121-A1 Precursor Compound of Radioactive Halogen-Labeled Organic Compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2008-11-13 US disclosed
EP-1978015-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD. (JP) 2008-10-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180256760-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 SYK 2305/4885AKT1 1758/4885EPHX2 3113/4885
US-11083804-B2 Precursor compound of radioactive halogen-labeled organic compound BCAT2, SLCO2B1, ORC3 SYK 2305/4885AKT1 1758/4885EPHX2 3113/4885
US-20210386873-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 SYK 2305/4885AKT1 1758/4885EPHX2 3113/4885
US-20100016626-A1 PROCESS FOR PRODUCTION OF PRECURSOR COMPOUND FOR RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND FUS, SLC43A1, PFAS SYK 3761/4885AKT1 1756/4885EPHX2 4033/4885
US-20090198085-A1 Process for Production of Radioactive Fluorine-Labeled Organic Compound FOSB, AFF1, SLCO4C1 SYK 2993/4885AKT1 1776/4885EPHX2 3141/4885
US-20100261931-A1 PROCESS FOR PRODUCTION OF RADIOACTIVE-FLUORINE-LABELED ORGANIC COMPOUND AFF1, SLCO4C1, SLCO2A1 SYK 1064/4885AKT1 1102/4885EPHX2 3456/4885
US-20080281121-A1 Precursor Compound of Radioactive Halogen-Labeled Organic Compound BCAT2, SLCO2B1, ORC3 SYK 2305/4885AKT1 1758/4885EPHX2 3113/4885
US-20200282082-A1 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND BCAT2, SLCO2B1, ORC3 SYK 2305/4885AKT1 1758/4885EPHX2 3113/4885
US-10953112-B2 Precursor compound of radioactive halogen-labeled organic compound BCAT2, SLCO2B1, ORC3 SYK 2305/4885AKT1 1758/4885EPHX2 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.