Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15580679 | 0.90 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL473929 | 0.89 | ALDH1A1 (0.35) | ALDH1A1PTGER3USP30L3MBTL1GPR55 | |
| SCHEMBL12163913 | 0.89 | ALDH1A1 (0.35) | ALDH1A1PTGER3USP30L3MBTL1GPR55 | |
| SCHEMBL473937 | 0.87 | ALDH1A1 (0.35) | ALDH1A1PTGER3USP30L3MBTL1GPR55 | |
| SCHEMBL12163734 | 0.87 | ALDH1A1 (0.35) | ALDH1A1PTGER3USP30L3MBTL1GPR55 | |
| SCHEMBL15580707 | 0.86 | PTGER3 (0.32) | ALDH1A1PTGER3USP30L3MBTL1GPR55 | |
| SCHEMBL473891 | 0.83 | KMO (0.40) | ALDH1A1PTGER3 | |
| SCHEMBL12163917 | 0.83 | KMO (0.40) | ALDH1A1PTGER3 | |
| SCHEMBL474720 | 0.82 | PTGER3 (0.33) | ALDH1A1PTGER3USP30L3MBTL1GPR55 | |
| SCHEMBL473945 | 0.82 | ALDH1A1 (0.38) | ALDH1A1PTGER3USP30L3MBTL1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411365-B1 | 2,3-DIARYL- OR HETEROARYL-SUBSTITUTED 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2014-03-19 | — | — | EP | disclosed |