Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 1.00 |
| ▸ | CPA3 | P15088 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CPA1 | P15085 | 2/20 | 0.66 |
| ▸ | CPB1 | P15086 | 1/20 | 0.66 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.66 |
| ▸ | MME | P08473 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464853 | 1.00 | FOLH1 (1.00) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL4664822 | 0.87 | CYP1A2 (1.00) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL9622038 | 0.85 | CYP1A2 (0.86) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL9875948 | 0.85 | CYP1A2 (0.95) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL22115491 | 0.85 | CYP1A2 (0.95) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL27291058 | 0.85 | CYP1A2 (0.95) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL7439697 | 0.85 | CYP1A2 (0.86) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL7432418 | 0.85 | CYP1A2 (0.86) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL5054419 | 0.84 | FOLH1 (0.80) | FOLH1CPA3CYP1A2CPA1CPB1 | |
| SCHEMBL10038980 | 0.84 | CPA3 (0.72) | FOLH1CPA3CYP1A2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942468-A | A kind of process preparing cadotril by 3- phenyl -1- propine | 大连万福制药有限公司 | 2019-06-28 | — | — | CN | claimed |
| US-20060089503-A1 | Processes for producing optically active 2-thiomethyl-3-phenylpropionic acid derivative and for producing intermediate therefor | KANEKA CORPORATION (JP) | 2006-04-27 | — | — | US | claimed |
| EP-1577310-A1 | PROCESSES FOR PRODUCING OPTICALLY ACTIVE 2-THIOMETHYL-3-PHENYLPROPIONIC ACID DERIVATIVE AND FOR PRODUCING INTERMEDIATE THEREFOR | KANEKA CORPORATION (JP) | 2005-09-21 | — | — | EP | claimed |
| US-6395718-B1 | RHEUMATIC DISEASES; ANTIARTHRITIC AGENTS; CARDIOVASCULAR DISORDERS | GUILFORD PHARMACEUTICALS INC. | 2002-05-28 | — | — | US | claimed |
| EP-0820439-B1 | METHOD FOR THE ASYMMETRICAL SYNTHESIS OF S-ACYLATED DERIVATIVES OF 2-MERCAPTOMETHYL 3-PHENYL PROPANOIC ACID, AND USE THEREOF FOR SYNTHESISING N-(MERCAPTOACYL) AMINO ACID DERIVATIVES | BIOPROJET SOC CIV (FR) | 2000-05-03 | — | — | EP | claimed |
| US-6013829-A | REDUCING A MALONIC DIESTER, HYDRIDING TO OBTAIN A DIOL, ACETYLATING TO OBTAIN A MONOESTER, OXIDATION, SAPONIFICATION AND THIOACYLATING; ENZYME INHIBITORS; PROTEASES; OPTICS; ANTISECRETORY AND HYPOTENSIVE AGENTS | SOCIETE CIVILE BIOPROJET (FR) | 2000-01-11 | — | — | US | claimed |
| EP-2303929-B1 | A MACROCYCLIC DERIVATIVE AND ASSEMBLIES FORMED THEREFROM | UNIV COLLEGE DUBLIN NAT UNIV IRELAND DUBLIN (IE) | 2024-10-02 | — | — | EP | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| CN-110156820-B | Mercaptoamide boronic acid derivatives and application thereof as MBL (sodium Bromide) and/or SBL (SBL) inhibitor | 四川大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-108430968-B | Industrial process for the preparation of (5S,10S) -10-benzyl-16-methyl-11, 14, 18-trioxo-15, 17, 19-trioxa-2, 7, 8-trithia-12-azaheneicosane-5-ammonium (E) -3-carboxy acrylate | 领先药物公司 | 2021-01-05 | — | — | CN | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| EP-0820439-A1 | METHOD FOR THE ASYMMETRICAL SYNTHESIS OF S-ACYLATED DERIVATIVES OF 2-MERCAPTOMETHYL 3-PHENYL PROPANOIC ACID, AND USE THEREOF FOR SYNTHESISING N-(MERCAPTOACYL) AMINO ACID DERIVATIVES | SOCIETE CIVILE BIOPROJET (FR) | 1998-01-28 | — | — | EP | disclosed |
| WO-1997029086-A1 | METHOD FOR THE ASYMMETRICAL SYNTHESIS OF S-ACYLATED DERIVATIVES OF 2-MERCAPTOMETHYL 3-PHENYL PROPANOIC ACID, AND USE THEREOF FOR SYNTHESISING N-(MERCAPTOACYL) AMINO ACID DERIVATIVES | SOCIETE CIVILE BIOPROJET (FR) | 1997-08-14 | — | — | WO | disclosed |
| US-5486596-A | CYCLIC PEPTIDES | CESKOSLOVENSKA AKADEMIE VED (CS) | 1996-01-23 | — | — | US | disclosed |
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4513009-A | GLYCINE, ALANINE AND SERINE DERIVATIVES | SOCIETE CIVILE BIOPROJET (FR) | 1985-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089503-A1 | Processes for producing optically active 2-thiomethyl-3-phenylpropionic acid derivative and for producing intermediate therefor | NOTUM, FAR1, ALDH7A1 | FOLH1 186/4885CPA3 2409/4885CYP1A2 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.