Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004075 | 0.83 | MEN1 (0.44) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL27878369 | 0.82 | KDM4E (0.44) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL28248982 | 0.79 | KDM4E (0.40) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL5524083 | 0.79 | KDM4E (0.40) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL25786462 | 0.79 | KDM4E (0.40) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL28650262 | 0.79 | KDM4E (0.42) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL24854679 | 0.77 | KDM4E (0.43) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL28068652 | 0.76 | CYP2A6 (0.43) | KDM4ELMNACYP2A6USP2ALDH1A1 | |
| SCHEMBL28865511 | 0.76 | KDM4E (0.40) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL27878373 | 0.76 | CYP2A6 (0.39) | KDM4ELMNACYP2A6USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083927-B | Phosphino- amidine compound, metal complex, antigravity system and their oligomeric or olefin polymerization purposes | 切弗朗菲利浦化学公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-106083927-A | Phosphinyl amidine compound, metal complex, antigravity system and their oligomeric or purposes of olefin polymerization | 切弗朗菲利浦化学公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-102781949-B | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins | 切弗朗菲利浦化学公司 | 2016-07-06 | — | — | CN | disclosed |
| WO-2014144545-A2 | SUBSTITUTED BENZOXAZOLES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014008458-A2 | N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2014-01-09 | — | — | WO | disclosed |
| CN-102781949-A | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins | CHEVRON PHILLIPS CHEMICAL CO | 2012-11-14 | — | — | CN | disclosed |