Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13758477 | 0.88 | CYP2A6 (0.37) | CYP2A6HSPA5KDM4EALDH1A1GAA | |
| SCHEMBL19774132 | 0.86 | ALDH1A1 (0.39) | CYP2A6KDM4EALDH1A1GAAMAPT | |
| SCHEMBL28248942 | 0.85 | KDM4E (0.35) | CYP2A6KDM4EALDH1A1GAAMAPT | |
| SCHEMBL28068726 | 0.85 | ALDH1A1 (0.41) | CYP2A6KDM4EALDH1A1GAAMAPT | |
| SCHEMBL28248920 | 0.81 | KDM4E (0.33) | CYP2A6KDM4EALDH1A1GAAMAPT | |
| SCHEMBL2154515 | 0.81 | CYP2A6 (0.43) | CYP2A6KDM4EALDH1A1GAAMAPT | |
| SCHEMBL16883661 | 0.81 | KDM4E (0.41) | CYP2A6KDM4EALDH1A1GAAMAPT | |
| SCHEMBL1427328 | 0.79 | KDM4E (0.36) | CYP2A6KDM4EALDH1A1GAAMAPT | |
| SCHEMBL17968440 | 0.78 | HSPA5 (0.35) | CYP2A6HSPA5GAAMEN1KMT2A | |
| Acetonitrile SCHEMBL11807238 | 0.77 | RAB9A (0.39) | ALDH1A1MAPTHPGDHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083927-A | Phosphinyl amidine compound, metal complex, antigravity system and their oligomeric or purposes of olefin polymerization | 切弗朗菲利浦化学公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-102781949-B | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins | 切弗朗菲利浦化学公司 | 2016-07-06 | — | — | CN | disclosed |