Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599542 | 0.87 | NAMPT (0.56) | NAMPTCA1CA2MAPTTDP1 | |
| SCHEMBL13497484 | 0.85 | TDP1 (0.56) | NAMPTL3MBTL1CA1CA2GAA | |
| SCHEMBL3180689 | 0.84 | L3MBTL1 (0.61) | NAMPTL3MBTL1CA1CA2GAA | |
| SCHEMBL24124249 | 0.83 | NAMPT (0.53) | NAMPTL3MBTL1CA1CA2GAA | |
| SCHEMBL25920561 | 0.83 | NAMPT (0.59) | NAMPTL3MBTL1CA1CA2MAPT | |
| SCHEMBL11090977 | 0.83 | NAMPT (0.53) | NAMPTL3MBTL1CA1CA2GAA | |
| SCHEMBL732456 | 0.82 | NAMPT (0.57) | NAMPTL3MBTL1CA1CA2GAA | |
| SCHEMBL5459163 | 0.81 | CYP17A1 (0.57) | NAMPTL3MBTL1CA1CA2GAA | |
| SCHEMBL4252911 | 0.80 | NAMPT (0.55) | NAMPTL3MBTL1CA1CA2GAA | |
| SCHEMBL1444314 | 0.80 | HPGD (0.59) | NAMPTL3MBTL1CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895204-B1 | COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2020-10-21 | — | — | EP | disclosed |
| US-10039846-B2 | Compositions targeting bradykinin receptor B1 for medical imaging of cancer and other disorders | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2018-08-07 | — | — | US | disclosed |
| US-10039846-B2 | Compositions targeting bradykinin receptor B1 for medical imaging of cancer and other disorders | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2018-08-07 | — | — | US | disclosed |
| US-20150238641-A1 | COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2015-08-27 | — | — | US | disclosed |
| US-20150238641-A1 | COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2015-08-27 | — | — | US | disclosed |
| WO-2014040192-A1 | COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2014-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238641-A1 | COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS | BDKRB1, BDKRB2, VIPR1 | NAMPT 1691/4885L3MBTL1 1287/4885CA1 3116/4885 |
| US-10039846-B2 | Compositions targeting bradykinin receptor B1 for medical imaging of cancer and other disorders | BDKRB1, BDKRB2, EDNRB | NAMPT 2155/4885L3MBTL1 1654/4885CA1 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.