SCHEMBL15599404

SCHEMBL15599404

COc1ccc(-c2ccc(-c3ccc(O)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 1.00
LTA4H P09960 1/20 0.73
ABL1 P00519 2/20 0.71
ABCB1 P08183 2/20 0.71
BCR P11274 2/20 0.71
NPC1 O15118 2/20 0.71
TP53 P04637 1/20 0.71
MAPK1 P28482 1/20 0.71
CASP3 P42574 1/20 0.71
RAB9A P51151 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
SENP8 Q96LD8 1/20 0.71
SENP7 Q9BQF6 1/20 0.71
SENP6 Q9GZR1 1/20 0.71
APP P05067 2/20 0.69
CALM1 P0DP23 1/20 0.59
GAA P10253 1/20 0.59
PKM P14618 1/20 0.59
ESR1 P03372 1/20 0.58
CA12 O43570 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1341494 1.00 ESR2 (1.00) ESR2LTA4HABL1ABCB1BCR
SCHEMBL28162733 0.97 ESR2 (0.95) ESR2LTA4HABL1ABCB1BCR
SCHEMBL26766402 0.93 LTA4H (0.86) ESR2LTA4HABL1ABCB1BCR
SCHEMBL20060980 0.93 ESR2 (0.86) ESR2LTA4HABL1ABCB1BCR
SCHEMBL20060981 0.93 ESR2 (0.86) ESR2LTA4HABL1ABCB1BCR
Mequinol SCHEMBL1535640 0.92 ESR2 (0.84) ESR2LTA4HABL1ABCB1BCR
Mequinol SCHEMBL21009 0.92
1,4-Dimethoxybenzene SCHEMBL8351066 0.92 ESR2 (0.84) ESR2LTA4HABL1ABCB1BCR
Mequinol SCHEMBL166535 0.92 ESR2 (0.84) ESR2LTA4HABL1ABCB1BCR
SCHEMBL5190092 0.91 ESR2 (0.83) ESR2LTA4HABL1ABCB1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847809-B1 OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS LOMOX LTD (GB) 2017-12-20 EP disclosed
WO-2013167857-A1 OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS LOMOX LIMITED (GB) 2013-11-14 WO disclosed