SCHEMBL15599700

SCHEMBL15599700

Clc1ccc2[nH]c3ccc(Br)cc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 2/20 0.53
AR P10275 1/20 0.47
LMNA P02545 2/20 0.47
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
GAA P10253 1/20 0.46
HTR2A P28223 2/20 0.45
HTR2C P28335 2/20 0.45
HTR2B P41595 2/20 0.45
PIM3 Q86V86 1/20 0.45
MGLL Q99685 1/20 0.45
MAP4K1 Q92918 1/20 0.45
MAPT P10636 2/20 0.44
ERBB2 P04626 1/20 0.43
PTK6 Q13882 1/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
PTGS2 P35354 2/20 0.43
MEN1 O00255 1/20 0.43
ABCC4 O15439 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29923100 1.00 CHUK (0.53) CHUKARLMNAHPGDCYP1A2
SCHEMBL18212083 0.90 CHUK (0.53) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL18203478 0.90 CHUK (0.53) CHUKARLMNAHPGDPIM3
SCHEMBL30981753 0.89 LMNA (0.50) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL29366993 0.87 CHUK (0.64) CHUKARLMNAHPGDCYP1A2
SCHEMBL38602 0.87 CHUK (0.64) CHUKARLMNAHPGDCYP1A2
SCHEMBL607827 0.87 CHUK (0.64) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL29453525 0.87 CHUK (0.64) CHUKLMNAHPGDCYP1A2GAA
SCHEMBL17747410 0.85 AHR (0.46) CHUKARMAPTPTGS2MEN1
SCHEMBL28288154 0.84 CHUK (0.62) CHUKARLMNAHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4629980-A1 ANTIMICROBIAL COMPOUNDS SRI International (US) 2025-10-15 EP disclosed
WO-2024123663-A1 ANTIMICROBIAL COMPOUNDS SRI INTERNATIONAL (US) 2024-06-13 WO disclosed
WO-2024123663-A1 ANTIMICROBIAL COMPOUNDS SRI INTERNATIONAL (US) 2024-06-13 WO disclosed
CN-114736198-B Organic compound, and electronic element and electronic device using same 陕西莱特光电材料股份有限公司 2023-11-03 CN disclosed
CN-114736198-A Organic compound, and electronic element and electronic device using same 陕西莱特光电材料股份有限公司 2022-07-12 CN disclosed
CN-111848492-B Organic compound, and device and electronic device using same 陕西莱特光电材料股份有限公司 2021-05-18 CN disclosed
CN-111848492-A Organic compound, and device and electronic device using same 陕西莱特光电材料股份有限公司 2020-10-30 CN disclosed
WO-2017188597-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2017-11-02 WO disclosed
WO-2017111543-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2017-06-29 WO disclosed
WO-2014031986-A1 PRO-NEUROGENIC COMPOUNDS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-02-27 WO disclosed