Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564543 | 0.89 | MTNR1A (0.53) | MTNR1ATSHRPLA2G4BMTNR1BSMPD1 | |
| SCHEMBL2096277 | 0.84 | TSHR (0.53) | MTNR1ATSHRPLA2G4BSMPD1 | |
| SCHEMBL10363484 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL8724311 | 0.82 | NR5A1 (0.55) | MTNR1ATSHRPLA2G4B | |
| SCHEMBL2096275 | 0.82 | TSHR (0.51) | MTNR1ATSHRPLA2G4BSMPD1 | |
| SCHEMBL249286 | 0.82 | KCNA3 (0.55) | TSHR | |
| SCHEMBL3844038 | 0.82 | TSHR (0.48) | MTNR1ATSHRPLA2G4BSMPD1 | |
| SCHEMBL13243533 | 0.81 | MTNR1A (0.47) | MTNR1ATSHRPLA2G4BMTNR1B | |
| SCHEMBL13243531 | 0.81 | MTNR1A (0.47) | MTNR1ATSHRPLA2G4BMTNR1B | |
| SCHEMBL13243530 | 0.81 | MTNR1A (0.47) | MTNR1ATSHRPLA2G4BMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025709-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-02-13 | — | — | WO | disclosed |