Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.51 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23157239 | 0.97 | DPP8 (0.55) | SLC1A3SLC1A1DPP8DPP7SLC1A5 | |
| SCHEMBL2037306 | 0.86 | SLC1A3 (0.70) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| SCHEMBL2677967 | 0.86 | SLC1A3 (0.70) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| SCHEMBL4986552 | 0.86 | SLC1A3 (0.70) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| Hydrochloric Acid SCHEMBL6751263 | 0.85 | SLC1A3 (0.69) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| Hydrochloric Acid SCHEMBL29025567 | 0.85 | SLC1A3 (0.69) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| Hydrochloric Acid SCHEMBL5652476 | 0.85 | SLC1A3 (0.69) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| SCHEMBL18541541 | 0.84 | DPP8 (0.56) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| Hydrochloric Acid SCHEMBL20945356 | 0.83 | DPP8 (0.55) | SLC1A3SLC1A1DPP8DPP7ANPEP | |
| Hydrochloric Acid SCHEMBL20945357 | 0.83 | DPP8 (0.55) | SLC1A3SLC1A1DPP8DPP7ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062028-B2 | Bicyclic nitrogen containing heteroaryl TGR5 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-06-23 | — | — | US | disclosed |
| US-20140080788-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080788-A1 | NOVEL BICYCLIC NITROGEN CONTAINING HETEROARYL TGR5 RECEPTOR MODULATORS | GRK5, GPBAR1, GPR55 | SLC1A3 1037/4885SLC1A1 1169/4885DPP8 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.