Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.56 |
| ▸ | YES1 | P07947 | 4/20 | 0.56 |
| ▸ | FGR | P09769 | 4/20 | 0.56 |
| ▸ | BTK | Q06187 | 10/20 | 0.48 |
| ▸ | FYN | P06241 | 4/20 | 0.47 |
| ▸ | LYN | P07948 | 3/20 | 0.47 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.47 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 5/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 3/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | FRK | P42685 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | BMX | P51813 | 3/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613540 | 0.94 | BTK (0.48) | SRCYES1FGRBTKFYN | |
| SCHEMBL15613692 | 0.93 | BTK (0.47) | SRCYES1FGRBTKFYN | |
| SCHEMBL15613698 | 0.90 | FGFR2 (0.46) | SRCYES1FGRBTKFYN | |
| SCHEMBL15613518 | 0.87 | BTK (0.53) | SRCYES1FGRBTKFYN | |
| SCHEMBL15613510 | 0.86 | NUDT14 (0.63) | SRCBTKLYNNUDT14NUDT5 | |
| SCHEMBL15613548 | 0.85 | BTK (0.57) | SRCYES1FGRBTKFYN | |
| SCHEMBL19490391 | 0.85 | BTK (0.42) | SRCYES1FGRBTKFYN | |
| SCHEMBL15613547 | 0.85 | BTK (0.50) | SRCYES1FGRBTKFYN | |
| SCHEMBL16886172 | 0.81 | FGFR2 (0.47) | SRCYES1FGRBTKFYN | |
| SCHEMBL15613668 | 0.80 | BTK (0.66) | SRCYES1FGRBTKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2015-07-09 | — | — | US | disclosed |
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2015-07-09 | — | — | US | disclosed |
| WO-2013177668-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2013-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | TEC, SRC, LCK | SRC 2/4885YES1 39/4885FGR 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.