SCHEMBL156136

SCHEMBL156136

N#Cc1ccc(Br)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627845 1.00
Ammonia Solution, Strong SCHEMBL27701809 0.98 CHEK1 (0.42)
SCHEMBL5763859 0.84 MAOB (0.37)
SCHEMBL2008653 0.83 CHEK1 (0.45)
SCHEMBL4756228 0.76
SCHEMBL2327695 0.76
SCHEMBL20155217 0.76 CHEK1 (0.66)
SCHEMBL30270074 0.74 CHRNB2 (0.41)
SCHEMBL20644559 0.74 CHRNB2 (0.41)
SCHEMBL238425 0.73 NQO1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1835 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241497-A Preparation method of 5- (5-bromopyridine) tetrazole 上海若济生物医药科技有限公司 2025-01-03 CN claimed
CN-113603639-B Preparation method of 2-cyano-5-bromopyridine 黑龙江立科新材料有限公司 2023-06-27 CN claimed
CN-112939829-B Synthetic method of aryl trifluoromethyl thioether 武汉药明康德新药开发有限公司 2023-02-21 CN claimed
CN-115650908-A Preparation method of 5-bromo-2 cyanopyridine 南京康立瑞生物科技有限公司 2023-01-31 CN claimed
CN-112354551-B Monoatomic metal photocatalyst, preparation method thereof and application thereof in carbon-oxygen cross-coupling reaction 中国科学院化学研究所 2021-12-31 CN claimed
CN-113603639-A Preparation method of 2-cyano-5-bromopyridine 黑龙江立科新材料有限公司 2021-11-05 CN claimed
CN-112939829-A Synthetic method of aryl trifluoromethyl thioether 武汉药明康德新药开发有限公司 2021-06-11 CN claimed
CN-111302968-B Synthesis method of amide nitrogen trifluoromethyl compound 中国科学院上海有机化学研究所 2021-06-08 CN claimed
CN-112354551-A Novel monoatomic metal photocatalyst, preparation method thereof and application thereof in carbon-oxygen cross-coupling reaction 中国科学院化学研究所 2021-02-12 CN claimed
CN-111302968-A Synthesis method of amide nitrogen trifluoromethyl compound 中国科学院上海有机化学研究所 2020-06-19 CN claimed
US-12637454-B2 Heterocyclic monoacylglycerol lipase (MAGL) inhibitors HOFFMANN-LA ROCHE INC. (US) 2026-05-26 US disclosed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-4073062-B1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2026-04-29 EP disclosed
US-20260083674-A1 OXAZOLIDINONE LIPOSOME COMPOSITIONS AKAGERA MEDICINES, INC. (US) 2026-03-26 US disclosed
CN-121405620-B Synthesis method of 2-cyano-5-bromopyridine 山东佰隆医药有限公司 2026-03-20 CN disclosed
EP-0612313-A1 PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION GLAXO GROUP LIMITED (GB) 1994-08-31 EP disclosed
CN-1073433-A Cyclohexaneacetic acid derivatives GLAXO GROUP LTD (GB) 1993-06-23 CN disclosed
WO-1993010091-A2 PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION GLAXO GROUP LIMITED (GB) 1993-05-27 WO disclosed
EP-0542363-A2 Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation GLAXO GROUP LIMITED (GB) 1993-05-19 EP disclosed
EP-0537980-A1 Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation GLAXO GROUP LIMITED (GB) 1993-04-21 EP disclosed