Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16941526 | 0.89 | LMNA (0.67) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3051668 | 0.82 | LMNA (0.74) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3050959 | 0.76 | ALDH1A1 (0.67) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15614740 | 0.73 | MAPT (0.74) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15614741 | 0.73 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2TP53MAPTKMT2A | |
| SCHEMBL3048490 | 0.72 | LMNA (0.60) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3061283 | 0.71 | LMNA (0.58) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20570269 | 0.70 | TP53 (0.67) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3049996 | 0.70 | CYP1A2 (0.69) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15614742 | 0.70 | SMN1; SMN2 (0.59) | LMNAALDH1A1SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150210717-A1 | SPECIFIC INHIBITORS OF PROTEIN P21 AS THERAPEUTIC AGENTS | LEIBNIZ-INSTITUT FÜR ALTERSFORSCHUNG (DE) | 2015-07-30 | — | — | US | disclosed |
| WO-2014041125-A1 | SPECIFIC INHIBITORS OF PROTEIN P21 AS THERAPEUTIC AGENTS | BADEN-WÜRTTEMBERG STIFTUNG GMBH (DE) | 2014-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210717-A1 | SPECIFIC INHIBITORS OF PROTEIN P21 AS THERAPEUTIC AGENTS | CDKN1A, ING2, BCCIP | LMNA 2489/4885ALDH1A1 1754/4885CYP1A2 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.