Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29107134 | 0.86 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL2656032 | 0.84 | KMT2A (0.47) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| Hydrochloric Acid SCHEMBL30978679 | 0.81 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL2661779 | 0.81 | NPC1 (0.43) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL30978673 | 0.78 | SCD (0.46) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL30541530 | 0.77 | SCD (0.43) | KMT2AMEN1S1PR4ALDH1A1MAPT | |
| SCHEMBL31661625 | 0.75 | ALDH1A1 (0.51) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL15616483 | 0.73 | LTA4H (0.44) | NPC1RAB9AMAPTHTT | |
| SCHEMBL8789338 | 0.73 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9AS1PR4 | |
| SCHEMBL8437 | 0.73 | HTT (0.55) | KMT2AMEN1NPC1RAB9AS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014008214-A1 | BIARYL-CONTAINING COMPOUNDS AS INVERSE AGONISTS OF ROR-GAMMA RECEPTORS | BIOGEN IDEC MA INC. (US) | 2014-01-09 | — | — | WO | disclosed |