Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727922 | 0.85 | PARP1 (0.53) | PARP1HTR3AMAPTNPSR1RXFP1 | |
| SCHEMBL30573216 | 0.85 | PARP1 (0.53) | PARP1HTR3AMAPTNPSR1RXFP1 | |
| SCHEMBL13294905 | 0.83 | PARP1 (0.51) | PARP1HTR3AMAPTNPSR1RXFP1 | |
| SCHEMBL8550081 | 0.74 | PARP1 (0.43) | PARP1MAPT | |
| SCHEMBL8549330 | 0.74 | L3MBTL4 (0.45) | PARP1HTR3APTGS1PTGS2 | |
| SCHEMBL15427984 | 0.73 | CYP3A4 (0.39) | PARP1MAPTMAP2K1 | |
| SCHEMBL14686084 | 0.71 | PARP1 (0.42) | PARP1MAPTXDHSLC22A12CYP2A6 | |
| SCHEMBL9050184 | 0.70 | PARP1 (0.39) | PARP1 | |
| SCHEMBL1976575 | 0.69 | PARP1 (0.46) | PARP1 | |
| SCHEMBL7484709 | 0.69 | PARP1 (0.39) | PARP1CYP2A6PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014041140-A1 | METHODS OF TREATING HAIR RELATED CONDITIONS | NOGRA PHARMA LIMITED (IE) | 2014-03-20 | — | — | WO | disclosed |