Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15618082 | 0.85 | PDK2 (0.33) | TRPM8 | |
| SCHEMBL15618077 | 0.80 | PDK2 (0.34) | — | |
| SCHEMBL9811530 | 0.79 | CYP2C19 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14183710 | 0.79 | CYP2C19 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14463256 | 0.79 | CYP2C19 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14183683 | 0.76 | CYP2C19 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19135766 | 0.76 | NPSR1 (0.38) | TRPM8 | |
| SCHEMBL18753397 | 0.76 | NPSR1 (0.38) | TRPM8 | |
| SCHEMBL20814556 | 0.75 | TRPM8 (0.38) | TRPM8CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14183730 | 0.75 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679644-B2 | Electroluminescent polymers containing planar arylamine units, the preparation and use thereof | MERCK PATENT GMBH (DE) | 2014-03-25 | — | — | US | disclosed |