Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19135766 | 1.00 | NPSR1 (0.38) | NPSR1TRPM8ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19113988 | 0.85 | TRPM8 (0.33) | NPSR1TRPM8ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21653369 | 0.84 | NPSR1 (0.43) | NPSR1TRPM8ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL18400777 | 0.84 | NPSR1 (0.36) | NPSR1TRPM8ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL15499533 | 0.84 | NPSR1 (0.36) | NPSR1TRPM8ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL25804113 | 0.82 | FAAH (0.31) | FAAHPHGDHMGLL | |
| SCHEMBL20436369 | 0.80 | TRPM8 (0.32) | TRPM8 | |
| SCHEMBL22173846 | 0.80 | — | — | |
| SCHEMBL12158704 | 0.78 | ALDH1A1 (0.40) | TRPM8ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL24487234 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252624-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2802594-B1 | METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |