Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.72 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15619199 | 1.00 | MAOB (0.72) | MAOBARTNFRSF1AAURKANPSR1 | |
| SCHEMBL16948578 | 0.88 | MAOB (0.60) | MAOBARTNFRSF1AAURKANPSR1 | |
| SCHEMBL16928591 | 0.87 | MAOB (0.62) | MAOBARTNFRSF1AAURKANPSR1 | |
| SCHEMBL16928594 | 0.87 | MAOB (0.62) | MAOBARTNFRSF1AAURKANPSR1 | |
| SCHEMBL5084246 | 0.86 | AURKA (0.69) | MAOBTNFRSF1AAURKACYP3A4MAPT | |
| SCHEMBL5084241 | 0.86 | AURKA (0.69) | MAOBTNFRSF1AAURKACYP3A4MAPT | |
| SCHEMBL19183469 | 0.84 | AURKA (0.66) | MAOBARAURKACYP3A4MAOA | |
| SCHEMBL19183470 | 0.84 | AURKA (0.66) | MAOBARAURKACYP3A4MAOA | |
| SCHEMBL19183188 | 0.84 | MAOB (0.72) | MAOBARAURKANPSR1MAPT | |
| SCHEMBL19183190 | 0.84 | MAOB (0.72) | MAOBARAURKANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629822-B2 | Flavonoid based antiviral targets | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150209323-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, (US) | 2015-07-30 | — | — | US | disclosed |
| WO-2014047551-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | UNIVERSITY OF CENTER FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209323-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | RBM28, MAVS, HAVCR2 | MAOB 4153/4885AR 4201/4885TNFRSF1A 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.