Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.72 |
| ▸ | AR | P10275 | 3/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.71 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.62 |
| ▸ | TFEB | P19484 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183190 | 1.00 | MAOB (0.72) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL26605004 | 0.90 | AURKA (0.61) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL30918537 | 0.90 | MAOB (0.69) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL26605033 | 0.89 | AURKA (0.60) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL19183398 | 0.89 | NFE2L2 (0.67) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL19183397 | 0.89 | NFE2L2 (0.67) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL16928592 | 0.86 | MAOB (0.59) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL16928593 | 0.86 | MAOB (0.59) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL16948581 | 0.86 | MAOB (0.58) | MAOBARNR1H4MAOANPC1 | |
| SCHEMBL19183469 | 0.86 | AURKA (0.66) | MAOBARNR1H4MAOAAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190008797-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-01-10 | — | — | US | disclosed |
| WO-2017132135-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190008797-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | ESRRG, GPER1, ESR2 | MAOB 3735/4885AR 143/4885NR1H4 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.