Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15619353 | 0.85 | CYP19A1 (0.59) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL8093207 | 0.84 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL8093202 | 0.84 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL11257429 | 0.81 | AR (0.61) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL7032375 | 0.78 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL7032379 | 0.78 | CYP19A1 (0.74) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL15951305 | 0.77 | CYP19A1 (0.60) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL27183317 | 0.76 | CYP19A1 (0.75) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL11246346 | 0.75 | MAOB (0.69) | CYP19A1MAOBMAPTNPC1RAB9A | |
| SCHEMBL11246350 | 0.75 | MAOB (0.69) | CYP19A1MAOBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629822-B2 | Flavonoid based antiviral targets | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150209323-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, (US) | 2015-07-30 | — | — | US | disclosed |
| WO-2014047551-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | UNIVERSITY OF CENTER FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209323-A1 | FLAVONOID BASED ANTIVIRAL TARGETS | RBM28, MAVS, HAVCR2 | CYP19A1 4345/4885MAOB 4153/4885MAPT 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.