3-Hydroxy-3',4'-Dimethoxyflavone

3-Hydroxy-3',4'-Dimethoxyflavone

SCHEMBL30139617

COc1ccc(-c2oc3ccccc3c(=O)c2O)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 1.00
CYP3A4 P08684 10/20 1.00
MAPT P10636 8/20 1.00
MEN1 O00255 8/20 1.00
KMT2A Q03164 8/20 1.00
ALDH1A1 P00352 7/20 1.00
TP53 P04637 7/20 1.00
HSD17B10 Q99714 7/20 1.00
HPGD P15428 6/20 1.00
CASP1 P29466 4/20 1.00
CASP7 P55210 4/20 1.00
LMNA P02545 4/20 1.00
ABCG2 Q9UNQ0 4/20 0.76
ABCB1 P08183 2/20 0.75
RXFP1 Q9HBX9 1/20 0.72
MAPK1 P28482 4/20 0.69
TSHR P16473 3/20 0.69
ALOX12 P18054 3/20 0.69
CYP2D6 P10635 3/20 0.69
CYP2C9 P11712 3/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL4285872 1.00 KDM4E (1.00) KDM4ECYP3A4MAPTMEN1KMT2A
3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL15676607 1.00 KDM4E (1.00) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL16237902 0.91 KDM4E (0.83) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL15844041 0.91 KDM4E (0.83) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL31031153 0.89 KDM4E (0.80) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL4649257 0.87 KDM4E (0.77) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL25235022 0.86 ABCB1 (0.79) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL30397364 0.86 ABCB1 (0.79) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL31675757 0.86 ABCB1 (1.00) KDM4ECYP3A4MAPTMEN1KMT2A
SCHEMBL4650613 0.86 ABCB1 (1.00) KDM4ECYP3A4MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119207584-A Computer-implemented method for evaluating plant nitrogen absorption capacity through rhizosphere soil environmental characteristics 贵州省蚕业研究所(贵州省辣椒研究所) 2024-12-27 CN claimed
CN-119207584-A Computer-implemented method for evaluating plant nitrogen absorption capacity through rhizosphere soil environmental characteristics 贵州省蚕业研究所(贵州省辣椒研究所) 2024-12-27 CN disclosed
CN-115501186-B Flavonol glycoside-citric acid solid dispersion and preparation method thereof 上海捌加壹医药科技有限公司 2023-08-04 CN disclosed
CN-115501186-A Flavonol glycoside-citric acid solid dispersion and preparation method thereof 上海捌加壹医药科技有限公司 2022-12-23 CN disclosed