SCHEMBL156202

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20232771	0.89	HRH3 (0.61)	HRH3ACHEALDH1A1MEN1KMT2A
	SCHEMBL8275450	0.85	HRH3 (0.76)	HRH3ACHEALDH1A1MEN1KMT2A
	SCHEMBL8252094	0.85	HRH3 (0.76)	HRH3ACHEALDH1A1MEN1KMT2A
	SCHEMBL17465246	0.84	HRH3 (0.69)	HRH3ACHEALDH1A1MEN1KMT2A
	SCHEMBL17828185	0.84	HRH3 (0.75)	HRH3ACHESIGMAR1
	SCHEMBL3861163	0.83	HRH3 (0.73)	HRH3ACHEALDH1A1SIGMAR1
	SCHEMBL3004249	0.83	HRH3 (0.73)	HRH3ACHEALDH1A1SIGMAR1CXCR3
	SCHEMBL5411899	0.83	HRH3 (0.73)	HRH3ACHEBCHEBACE1
	SCHEMBL6975680	0.83	HRH3 (0.73)	HRH3ACHEALDH1A1SIGMAR1BCHE
	SCHEMBL18908952	0.83	ACHE (0.62)	HRH3ACHEALDH1A1KDM4ESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.