Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10012149 | 0.90 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9811723 | 0.89 | CA1 (0.42) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL12954731 | 0.87 | CA1 (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL23515315 | 0.87 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL25735228 | 0.87 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL16705144 | 0.87 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL20757550 | 0.86 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL19337851 | 0.85 | TDP1 (0.47) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL22662486 | 0.85 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL26799152 | 0.85 | TDP1 (0.47) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680089-B2 | Fused pyridine derivatives | Xuanzhu Pharma Co., Ltd. (CN) | 2014-03-25 | — | — | US | disclosed |