SCHEMBL16705144

SCHEMBL16705144

CCCCC(CC)NC(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSK P43235 17/20 0.56
CTSS P25774 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23515315 1.00 CTSK (0.56) CTSKCTSS
SCHEMBL25735228 1.00 CTSK (0.56) CTSKCTSS
SCHEMBL27542782 0.95 CTSK (0.51) CTSKCTSS
Hydrochloric Acid SCHEMBL27541055 0.93 CTSK (0.50) CTSKCTSS
SCHEMBL28166713 0.93 CTSK (0.50) CTSKCTSS
SCHEMBL28470420 0.93 CTSK (0.50) CTSKCTSS
SCHEMBL28879680 0.93 CTSK (0.50) CTSKCTSS
SCHEMBL18122641 0.93 CTSK (0.50) CTSKCTSS
SCHEMBL29650147 0.92 CTSK (0.49) CTSKCTSS
SCHEMBL18644348 0.90 CTSK (0.56) CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044744-A2 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2024-02-29 WO disclosed
WO-2022140520-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS ESCIENT PHARMACEUTICALS, INC. (US) 2022-06-30 WO disclosed
WO-2020142557-A1 IRREVERSIBLE INHIBITORS OF MENIN-MLL INTERACTION BIOMEA FUSION, LLC (US) 2020-07-09 WO disclosed
EP-2524917-B1 FUSED PYRIDINE DERIVATIVES SIHUAN PHARMACEUTICAL HOLDINGS GROUP LTD (CN) 2018-06-27 EP disclosed
US-9029359-B2 Heteroaryl Btk inhibitors BIOGEN IDEC MA, INC. (US) 2015-05-12 US disclosed