Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DNTT | P04053 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867322 | 0.86 | PPARG (0.46) | ALDH1A1ALOX15TDP1TSHRUSP2 | |
| SCHEMBL11867328 | 0.86 | PPARG (0.46) | ALDH1A1ALOX15TDP1TSHRUSP2 | |
| SCHEMBL11866149 | 0.85 | PPARG (0.48) | ALDH1A1ALOX15TDP1CYP3A4TSHR | |
| SCHEMBL11866141 | 0.85 | PPARG (0.48) | ALDH1A1ALOX15TDP1CYP3A4TSHR | |
| SCHEMBL11866585 | 0.85 | DNTT (0.44) | ALDH1A1ALOX15TDP1TSHRUSP2 | |
| SCHEMBL11866575 | 0.85 | DNTT (0.44) | ALDH1A1ALOX15TDP1TSHRUSP2 | |
| SCHEMBL11867277 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ALOX15TDP1CYP3A4TSHR | |
| SCHEMBL11867281 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ALOX15TDP1CYP3A4TSHR | |
| SCHEMBL11867271 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ALOX15TDP1CYP3A4TSHR | |
| SCHEMBL11866493 | 0.75 | DNTT (0.50) | ALDH1A1PGRPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680327-B2 | Methods for manufacturing tetranor-prostaglandin D, J, E, A and F metabolites | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2014-03-25 | — | — | US | disclosed |