Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866575 | 1.00 | DNTT (0.44) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11867322 | 0.94 | PPARG (0.46) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11867328 | 0.94 | PPARG (0.46) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11866149 | 0.93 | PPARG (0.48) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11866141 | 0.93 | PPARG (0.48) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL15623626 | 0.85 | ALDH1A1 (0.37) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11866489 | 0.83 | DNTT (0.50) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11866493 | 0.83 | DNTT (0.50) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11869680 | 0.82 | TRPA1 (0.42) | DNTTPPARGPPARDPPARAALDH1A1 | |
| SCHEMBL11869689 | 0.82 | TRPA1 (0.42) | DNTTPPARGPPARDPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984455-A | Prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |