Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | SAT1 | P21673 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026422 | 0.89 | — | — | |
| SCHEMBL13999431 | 0.84 | CYP2D6 (0.41) | CYP2D6PLGPLATLMNASIGMAR1 | |
| SCHEMBL22886691 | 0.84 | CYP2D6 (0.41) | CYP2D6PLGPLATLMNASIGMAR1 | |
| SCHEMBL6878005 | 0.82 | — | — | |
| SCHEMBL11456185 | 0.80 | EPHX1 (0.41) | CYP2D6SIGMAR1KMT2A | |
| SCHEMBL7287796 | 0.77 | SIGMAR1 (0.37) | SIGMAR1TDP1SAT1 | |
| SCHEMBL18232481 | 0.77 | CYP2D6 (0.39) | CYP2D6PLGPLATLMNANCF1 | |
| SCHEMBL19780933 | 0.76 | CYP2D6 (0.48) | CYP2D6PLGPLATLMNANCF1 | |
| SCHEMBL23848106 | 0.75 | NCF1 (0.43) | SIGMAR1NCF1KDM1AMAOBKMT2A | |
| SCHEMBL11046913 | 0.74 | CYP2D6 (0.40) | CYP2D6PLGPLATLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710994-A1 | DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL REPAIR MATERIAL, AND CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| EP-2711381-A1 | NOVEL COMPOUND, COMPOSITION CONTAINING SAID COMPOUND, AND CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |