Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624144 | 1.00 | SPHK1 (0.41) | SPHK1ACEABCC4MAPTALDH1A1 | |
| SCHEMBL15624153 | 0.95 | ACE (0.38) | SPHK1ACEALDH1A1LMNA | |
| SCHEMBL5495114 | 0.94 | SPHK1 (0.42) | SPHK1ACEALDH1A1LMNA | |
| SCHEMBL16116975 | 0.90 | SPHK1 (0.43) | SPHK1 | |
| SCHEMBL15624148 | 0.90 | SPHK1 (0.43) | SPHK1 | |
| SCHEMBL15624158 | 0.90 | ACE (0.40) | ACELMNA | |
| SCHEMBL15624127 | 0.89 | SPHK1 (0.41) | SPHK1 | |
| SCHEMBL6881305 | 0.87 | SPHK1 (0.42) | SPHK1 | |
| SCHEMBL5495102 | 0.87 | SPHK1 (0.42) | SPHK1 | |
| SCHEMBL5495100 | 0.87 | SPHK1 (0.42) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| EP-2711351-A1 | Low catalyst loading in metathesis reactions | Evonik Industries AG (DE) | 2014-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | APEX1, PMS2, MAX | SPHK1 2084/4885ACE 385/4885ABCC4 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.