Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495102 | 1.00 | SPHK1 (0.42) | SPHK1FKBP1A | |
| SCHEMBL6881305 | 1.00 | SPHK1 (0.42) | SPHK1FKBP1A | |
| SCHEMBL15624127 | 0.99 | SPHK1 (0.41) | SPHK1FKBP1A | |
| SCHEMBL15624148 | 0.97 | SPHK1 (0.43) | SPHK1FKBP1A | |
| SCHEMBL16116975 | 0.95 | SPHK1 (0.43) | SPHK1FKBP1A | |
| SCHEMBL5496759 | 0.93 | SPHK1 (0.43) | SPHK1FKBP1A | |
| SCHEMBL6875002 | 0.93 | SPHK1 (0.43) | SPHK1FKBP1A | |
| SCHEMBL5496756 | 0.93 | SPHK1 (0.43) | SPHK1FKBP1A | |
| SCHEMBL20219229 | 0.92 | SPHK1 (0.41) | SPHK1FKBP1A | |
| SCHEMBL16116962 | 0.91 | FKBP1A (0.42) | SPHK1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743884-A1 | Progrugs to d-prolines | F.HOFFMANN-LA ROCHE AG (CH) | 2007-01-17 | — | — | EP | disclosed |
| US-6903129-B2 | D-proline prodrugs | HOFFMAN-LA ROCHE INC. (US) | 2005-06-07 | — | — | US | disclosed |
| EP-1458680-A1 | PRODRUGS TO D-PROLINES | F. Hoffmann-La Roche AG (CH) | 2004-09-22 | — | — | EP | disclosed |
| US-20030134891-A1 | New D-proline prodrugs | PENTRAXIN THERAPEUTICS LTD. (GB) | 2003-07-17 | — | — | US | disclosed |
| WO-2003051836-A1 | PRODRUGS TO D-PROLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134891-A1 | New D-proline prodrugs | PCNP, PREP, APP | SPHK1 1147/4885FKBP1A 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.