Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639644 | 0.81 | LMNA (0.39) | MAPTF10 | |
| SCHEMBL1640676 | 0.71 | F10 (0.40) | KDM4EMAPTF10 | |
| SCHEMBL1639790 | 0.71 | F10 (0.35) | KDM4EF10 | |
| SCHEMBL12727579 | 0.70 | GAA (0.42) | KDM4EMAPTF10 | |
| SCHEMBL3842545 | 0.69 | LMNA (0.38) | KDM4E | |
| SCHEMBL1639115 | 0.68 | F10 (0.42) | F10 | |
| SCHEMBL12727507 | 0.66 | NPC1 (0.41) | KDM4EMAPT | |
| SCHEMBL1640705 | 0.66 | F10 (0.36) | KDM4EF10 | |
| SCHEMBL12727585 | 0.66 | F10 (0.38) | F10 | |
| SCHEMBL14273367 | 0.66 | F10 (0.36) | KDM4EF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094272-B1 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARM INC (US) | 2014-03-26 | — | — | EP | disclosed |