SCHEMBL15626596

SCHEMBL15626596

COC(=O)c1cccc(OCC2CCN(c3ccccn3)CC2)c1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 9/20 0.55
SOAT1 P35610 2/20 0.55
CYP3A4 P08684 1/20 0.55
DRD4 P21917 3/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
F10 P00742 1/20 0.48
DRD2 P14416 2/20 0.47
SOAT2 O75908 1/20 0.46
DGAT2 Q96PD7 1/20 0.46
OPRD1 P41143 1/20 0.46
KCNH2 Q12809 1/20 0.46
FFAR1 O14842 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15610649 0.95 DGAT1 (0.51) DGAT1SOAT1CYP3A4DRD4MEN1
SCHEMBL14127722 0.85 DGAT1 (0.57) DGAT1SOAT1CYP3A4DRD4KMT2A
SCHEMBL670398 0.85 DGAT1 (0.57) DGAT1SOAT1CYP3A4DRD4KMT2A
SCHEMBL16661049 0.84 DGAT1 (0.56) DGAT1SOAT1CYP3A4SOAT2DGAT2
SCHEMBL14127752 0.83 DGAT1 (0.56) DGAT1SOAT1CYP3A4DRD4KMT2A
SCHEMBL16661302 0.82 DGAT1 (0.56) DGAT1SOAT1CYP3A4KMT2AF10
SCHEMBL15626638 0.82 DGAT1 (0.56) DGAT1SOAT1CYP3A4KMT2ASOAT2
SCHEMBL669645 0.82 DGAT1 (0.54) DGAT1SOAT1CYP3A4MEN1KMT2A
Potassium Ion SCHEMBL15610648 0.82 DGAT1 (0.54) DGAT1SOAT1CYP3A4KMT2ASOAT2
SCHEMBL20190433 0.82 NR1H4 (0.60) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140088124-A1 IMIDAZOLE DERIVATIVES INTERVET INC. 2014-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088124-A1 IMIDAZOLE DERIVATIVES DGAT1, DGAT2, SOAT1 DGAT1 1/4885SOAT1 3/4885CYP3A4 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.