Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 17/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15629943 | 0.90 | FDPS (0.51) | FDPSGGPS1 | |
| SCHEMBL15629875 | 0.86 | FDPS (0.40) | FDPSF2PRSS1PRSS2PRSS3 | |
| SCHEMBL15629895 | 0.85 | FDPS (0.47) | FDPSGGPS1 | |
| SCHEMBL15629915 | 0.84 | FDPS (0.46) | FDPS | |
| SCHEMBL15629923 | 0.83 | FDPS (0.45) | FDPS | |
| SCHEMBL15629896 | 0.82 | FDPS (0.43) | FDPS | |
| SCHEMBL15629882 | 0.80 | FDPS (0.42) | FDPS | |
| SCHEMBL15629924 | 0.80 | FDPS (0.42) | FDPS | |
| SCHEMBL12972897 | 0.79 | FDPS (0.56) | FDPSGGPS1 | |
| SCHEMBL15629897 | 0.77 | FDPS (0.43) | FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173946-B2 | Bifunctional hydroxy-bisphosphonic acid derivatives | ATLANTHERA (FR) | 2015-11-03 | — | — | US | disclosed |
| US-20140086843-A1 | BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | ATLANTHERA (FR) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140086843-A1 | BIFUNCTIONAL HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | BPGM, PHPT1, PTH1R | FDPS 275/4885F2 2113/4885PRSS1 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.